https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Exposure to perfluorooctanesulfonate (PFOS) but not perflurorooctanoic acid (PFOA) at ppb concentration induces chronic toxicity in Daphnia carinata https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46333 Daphnia carinata) using a battery of comprehensive toxicity tests, including a 48 h acute and a 21-day chronic assays. The survival, growth, and reproduction of D. carinata were monitored over a 21-day life cycle. PFOS exhibited higher toxicity than PFOA. The 48 h LC50 values (confidence interval) based on acute toxicity for PFOA and PFOS were 78.2 (54.9–105) mg L−1 and 8.8 (6.4–11.6) mg L−1, respectively. Chronic exposure to PFOS for 21 days displayed mortality and reproductive defects in D. carinata at a concentration as low as 0.001 mg L−1. Genotoxicity assessment using comet assay revealed that exposure for 96 h to PFOS at 1 and 10.0 mg L−1 significantly damaged the organism's genetic makeup. The results of this study have great implications for risk assessment of PFOS and PFOA in aquatic ecosystems, given the potential of PFOS to pose a risk to Daphnia even at lower concentrations (1 μg L−1).]]> Tue 15 Nov 2022 12:49:03 AEDT ]]> Perfluorooctanoic acid (PFOA) induces behavioural, reproductive and developmental toxicological impacts in Caenorhabditis elegans at concentrations relevant to the contaminated areas https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:43866 Tue 04 Oct 2022 12:28:33 AEDT ]]>